The appeal of VRMMO novels sort of lies in their low stakes aspect. Most, if not all, of them tend to be Slice of Life, so the theme suits it well.
Interestingly, the difference between an isekai and VRMMO protagonist is minimal aside from the genre. They'd make the same choice in a similar situation, even if the stakes were totally different.
However, I think it is more consistent, for you wouldn't want to engage in a battle with a dragon even in a fantasy world. The protagonist would need a compelling reason, which is something this genre is exempt from. Also, due to the low stakes, it challenges the author to establish why readers should care about the story, and while they may not always succeed, the result is more favorable than poorly written isekai works.
VRMMO mimics real life but is ultimately a game, so game logic prevails, wherein a fantasy world is a real world. So certain things in isekai, like stats, skills, level, economy, and consequential decision-making, make less sense in the context of VRMMOs. Plus you don't have to deal with stuff like slavery.
Conclusion: If you are bored of the same life-and-death stake stories, or simply looking for a cozy adventure with a dash of adventure and action, VRMMO stories are a fine choice, in my opinion.