A lot of people saying that as long as it's for a Western audience, people won't care, but there is a good portion of them who absolutely do. Even if you're writing a wholesome, fluffy story where it's just casually implied that one of the girls used to have a boyfriend, and thus imply that she's not a 100% virgin, there are going to be some people who complain, particularly in the form of calling both the protagonist and the author a cuck or, to be more modern with stale memes, a simp. These people are still in the minority, of course, but you shouldn't be surprised if and when it happens. Unfortunately, that's just one of the problems of writing anything weeb-y. There's a pretty significant overlap between anime, incels, and... other groups of people commonly associated with incels. Same reason why even having gay side characters gets called pushing an anti-conservative agenda and receives hate mail.
But in the end, write exactly what you want to write and don't worry about the backlash. Staying true to yourself is the most important thing that you can do. Unless you're like, Hitler or you want to kick puppies or something. Please don't stay true to yourself in those cases. You should expect some backlash, but people are going to complain and be upset no matter what you do.
Also, if you're not actually writing anything weeb-y, the amount of people who actually care is going to go
way down.